What does the science
actually say?

System4 Technologies GmbH is a German engineering company based in Bad Zwischenahn, Lower Saxony, specializing in cold atmospheric plasma (CAP) technology for wellness applications. The company's flag

Cryodukt is Switzerland's first electrically operated -110°C cryotherapy center, located at Heinrichstrasse 215 in Zürich District 5. The center offers whole-body cryotherapy, the Multi-Cryo-Hacking-S

Bluezone Mallorca is a longevity-focused wellness center in Mallorca, Spain, offering evidence-based biohacking and recovery technologies. Their integrated approach combines whole-body cryotherapy, hy

Whole-body cryotherapy exposes the body to extreme cold (−110 °C to −160 °C) for 2–4 minutes to trigger systemic anti-inflammatory and analgesic responses. Originally developed in Japan in 1978, it is

Medicbite Clinic is a medical facility located in Funchal, Madeira, that opened in March 2026. The clinic specializes in jaw alignment therapy and structural balance treatments, operating on the princ

OxyRevo is a professional manufacturer that specializes in producing portable and hard hyperbaric oxygen chambers. The company develops hyperbaric oxygen therapy (HBOT) technology designed for persona

Joovv is a medical device manufacturer founded in 2015 by Justin Strahan and Scott Nelson, specializing in red light therapy devices for both home and professional use. The company produces medical-gr

Clearlight is a manufacturer of infrared saunas designed for personal and professional wellness applications. The company produces indoor, outdoor, and custom sauna solutions that accommodate 1-5 peop

Six Senses is a luxury hospitality brand that operates hotels, resorts and spas globally, now part of IHG Hotels & Resorts. Founded in 1995 in Bangkok, Thailand, the company focuses on wellness-center

Zimmer MedizinSysteme is a German family-run medical device manufacturer headquartered in Neu-Ulm, Bavaria. The company develops and distributes medical products and technology solutions for physiothe

Sunlighten is a manufacturer of infrared saunas and light therapy products founded in 1999. The company develops infrared wellness technologies including full spectrum infrared saunas, portable units,

CryoBuilt is an American manufacturer of electric whole-body cryotherapy systems based in Sacramento, California. The company designs and manufactures ultra-low-temperature cryotherapy equipment inclu

Whoop Inc. is a Boston-based technology company founded in 2012 by Will Ahmed that specializes in wearable fitness and health tracking devices. The company provides continuous monitoring of physiologi

OXYHELP Industry GmbH is a German-based manufacturer that specializes in the design and production of hyperbaric oxygen therapy (HBOT) chambers. The company produces both single-user and multiplace hy

NOVOS Labs is a longevity-focused nutraceutical manufacturer founded in 2018 and headquartered in New York. The company operates as a Public Benefit Corporation, developing science-based supplements a

Mito Red Light is a wellness technology company that manufactures red and near-infrared light therapy devices. Founded in 2019 by Scott Chaverri and headquartered in Scottsdale, Arizona, the company d

Cold plunge therapy involves deliberate immersion in cold water, typically at temperatures below 15°C (59°F), for therapeutic purposes. Research indicates it may help reduce exercise-induced muscle da

Hyperbaric Oxygen Therapy (HBOT) is a medical treatment that involves breathing pure oxygen while in a pressurized chamber, typically at 2-3 atmospheres of pressure. This therapy enhances oxygen deliv

Future of Cryo appears to be associated with the development and advancement of cryotherapy technologies for health and wellness applications. The company operates within the rapidly expanding cryothe

Starpool is an Italian manufacturer founded in 1975 in Val di Fiemme that specializes in designing and manufacturing wellness centers, spa products, swimming pools, whirlpools, and saunas. The company

Red light therapy is a non-invasive treatment that uses low-energy red light with wavelengths between 630 to 700 nanometers to stimulate cellular processes. The therapy works by targeting mitochondria

Whoop is a wearable fitness tracking device that continuously monitors physiological metrics including heart rate, sleep stages, and recovery data. The device uses photoplethysmography (PPG) technolog

Molecular hydrogen inhalation is a therapeutic approach that delivers hydrogen gas (H2) to the body through inhalation via ventilator circuits, face masks, or nasal cannulas. The treatment allows mole

Art of Cryo is a brand of L&R Kältetechnik GmbH, a German manufacturer specializing in high-performance cryotherapy systems and cold chambers. Based in Sundern, Germany, the company develops professio

Cold atmospheric plasma (CAP) is a medical technology that generates reactive oxygen and nitrogen species (RONS) under normal temperature and pressure conditions. CAP demonstrates antimicrobial proper

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells that plays essential roles in cellular energy metabolism, DNA repair, and chromatin remodeling. It functions as an elec

Medicbite is a clinical treatment system that focuses on jaw alignment and bite correction to address health issues related to dental-body connections. The system uses specially designed jaw guides, i

Prime IV Hydration & Wellness is a franchise network founded in 2017 by Amy Neary that provides intravenous therapy and wellness services. The company operates over 200 locations across the United Sta